Using Pill Buddy Naturals is super easy. First, take a Pill Buddy from the pair. Push your dog's pill or capsule into the treat, then squeeze it gently to make sure the pill is well - hidden. After that, just feed it to your dog. Since it's so tasty, your dog will likely gobble it up without a problem. As for storage, keep them in a cool and dry place. The wrapping is there to preserve freshness, so try not to open the pairs until you're ready to use them. There aren't any special handling requirements, but make sure to keep the treats out of reach of other pets or small children who might think they're regular snacks. Also, check the expiration date on the package to ensure the treats are still good. That's all you need to know to use Pill Buddy Naturals effectively for your dog's medicine time.