To use these DentaLife ActivFresh dog chews, simply give one to your medium-sized dog as a treat. These chews are designed to be chewed, which helps clean your dog's teeth and freshen their breath. As for precautions, make sure to keep an eye on your dog while they're chewing to prevent any choking hazards. Also, if your dog has any known allergies to honey or spirulina, it's best to consult your vet first. In terms of storage, keep the chews in a cool, dry place to maintain their quality. Don't leave them out in the open for too long, as they might get stale. That way, your dog can enjoy the fresh breath benefits for a long time.