Using GREENIES Dog Dental Treats is simple. Just give one treat to your dog once a day, preferably after a meal. These treats are suitable for dogs weighing 25 - 50 lbs (11 - 22 kgs). Make sure your dog has access to fresh water while enjoying the treat. Store the treats in a cool, dry place to keep them fresh. If your dog has any special dietary needs or health conditions, it's a good idea to consult your vet before giving these treats. Remember, these treats are a great addition to your dog's oral care routine, but they're not a substitute for regular vet check - ups.